分类: feed additives
作者: araujo, g., bach, a., mereu, a. and ipharraguerre, i.r.
出版物:xv jornadas sobre producción animal, zaragoza 14 y 15 de mayo de 2013 pp. 300-302
butyrate in the form of sodium butyrate (sb) is often used as an additive for milk replacers (mr) to improve calf and piglet performance. tributyrin (trb) is a triglyceride containing equivalent amounts of butyrate than sb but in a more stable form. thirty-six holstein calves (45.7±5.9 kg of bw and 11.9±3.0 d of age) were fed 4 l/d of mr and water and starter feed ad libitum. calves were randomly distributed in 2 groups. milk replacer was either unsupplemented (ctr) or supplemented with 3 g of tributyrin per kg of dm (trb). five calves per group were restricted at 200 g/d of starter and these calves were subjected to glucose tolerance tests (gtt) to assess resistance on days 0 and 42 of study. calves were blood-sampled every 14 d for glucose, insulin, glp-1 and bhba before and 60 min after the morning mr offer. calves in the ctr group showed better performance parameters. no differences were found in plasma glp-1, bhba, insulin, and glucose between treatments. however, evolution of plasma bhba along time tended to differ (p<0.08) because on day 14, plasma bhba concentration before and after mr feeding was similar for trb calves while ctr calves tended (p=0.06) to have a lesser concentration after mr. evolution of plasma glucose and insulin across time also differed (p<0.001 and p<0.001, respectively) between treatments. plasma glucose after morning mr take increased later (p<0.05) in time in trb than in ctr calves; but ctr calves had greater (p<0.05) insulin levels on day 14 than 28. results from the gtt showed that glucose peak and gcr on day 42 were greater (p<0.05) for trb than for c calves (3.5 vs 5.8±0.69 mmol/l and 4.6 vs 17.3±3.09 mmol/lxmin; respectively) which indicates a different insulin secretion pattern between treatments. in conclusion, these results demonstrate that butyrate supplementation in the form of tributyrin at 3 g/kg of mr modulates glucose and insulin hemodynamic but does not alter bhba and glp-1 plasma concentration nor increases performance.